Final answer:
Methacholine doesn't have a negative impact on the autonomic system, rather it stimulates a specific response which is used in diagnoses. Its effect cannot be eliminated but can be minimized with a smaller dose or pre-treatment with other medication under careful medical guidance.
Step-by-step explanation:
Methacholine is commonly used in diagnosing asthma, as it is a drug that works on the parasympathetic (autonomic) nervous system to constrict the airways. In terms of its effect on the function of the autonomic system, it doesn't have a negative impact rather, it has a specific intended impact to stimulate a response in the system.
Improving methacholine for future studies, the impact cannot be entirely eliminated because it would then fail to serve its diagnostic purpose. However, the 'impact' or 'effect' can potentially be minimized if a smaller dose is used, or if the patient is pretreated with a bronchodilator medication. Always, it's important to remember that changes in protocol like these should only be done under professional medical guidance and must be carefully studied for both safety and effectiveness.
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