False. The NASA Revitalization Act of 2010 primarily focused on the revitalization of NASA's programs and objectives, rather than addressing the safe and efficient operations of Unmanned Aircraft Systems (UAS) in the National Airspace System (NAS). The legislation did not specifically lay the groundwork for UAS operations in the NAS. However, NASA has been involved in various research and development activities related to UAS and their integration into the airspace, but those efforts were not specifically driven by the 2010 Revitalization Act.