The infusion rate can be calculated using the following formula:
Infusion rate (mL/hour) = Total volume (mL) ÷ Total time (minutes) x 60
Substituting the given values, we get:
Infusion rate (mL/hour) = 500 mL ÷ 300 minutes x 60
Infusion rate (mL/hour) = 10 mL/minute x 60
Infusion rate (mL/hour) = 600 mL/hour
Therefore, the NS should be infused at a rate of 600 mL/hour using an IV pump.