Methotrexate- induced senescence of human colon cancer cells depends on p53 acetylation, but not genomic aberrations.

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asked Nov 12, 2024 44.8k views

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Neil Stockton · Answer 1 · 2024-11-17T02:31:33+0000

This means methotrexate doesn't cause mutations or other genomic aberration but rather induce senescence through a finding p53 acetylation. This helps for cancer treatment that affect senescence pathways

Methotrexate- induced senescence of human colon cancer cells depends on p53 acetylation, but not genomic aberrations.

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