Step-by-step explanation:
According to a study published in the Journal of Obstetrics and Gynaecology Research, vaginal administration of misoprostol can soften the cervix within 6 hours in some cases. However, it may take up to 24 hours for the cervix to fully soften and dilate. The study also found that higher doses of misoprostol were associated with a shorter time to cervical softening.
Another study published in the Journal of Family Medicine and Primary Care found that oral administration of misoprostol can also effectively soften the cervix before medical procedures. The study reported that cervical softening occurred within 4-6 hours after oral administration of misoprostol.