Eliquis is the brand name for the apixaban, an anticoagulant medication found within the Factor Xa inhibitor pharmacological class indicated for risk mitigation of stroke and systemic embolism associated with nonvalvular A-fib, DVT prophylaxis following knee or hip replacement, and treatment of or risk reduction for DVT and PEs. It works by preventing thromboembolic events without directly affecting platelet aggregation, instead opting to do so indirectly via thrombin inhibition.