In response to increased blood calcium levels, calcitonin activates osteoblasts and inhibits osteoclasts. This hormone promotes bone formation by stimulating osteoblasts to build new bone tissue. By activating osteoblasts, calcitonin helps to lower blood calcium levels by promoting calcium deposition in bone.
On the other hand, calcitonin inhibits osteoclasts, which are responsible for bone resorption. By inhibiting osteoclast activity, calcitonin helps to prevent excessive breakdown of bone tissue and the release of calcium into the bloodstream. This inhibition of osteoclasts aids in maintaining bone homeostasis and prevents a further increase in blood calcium Increased Blood Calcium Levels
Diagram of the regulatory mechanism triggering changes in bone-cell activity:
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Release of Calcitonin
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Activation of Osteoblasts Inhibition of Osteoclasts
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Bone Formation Decreased Bone Resorption levels.
This diagram represents the regulatory mechanism in response to increased blood calcium levels. When blood calcium levels rise, the thyroid gland releases calcitonin. Calcitonin then acts on bone cells, activating osteoblasts and inhibiting osteoclasts. This results in increased bone formation by osteoblasts and decreased bone resorption by osteoclasts. These combined actions help to lower blood calcium levels and maintain bone homeostasis.