Which of the following correctly describe a feature of how enzymes function as reaction catalysts? Choose one or more: O A. Some of the amino acids in an enzyme's active site play a direct role in lowering the activation energy of the given reaction. B. Most enzymes contain multiple protein subunits C. Enzymes function primarily by lowering the activation energy of a reaction in order to speed up O O the rate of the reaction. D. Adding the suffix"-ase" to the end of a protein's name denotes that the protein is an enzyme.