Final answer:
True, large veins, medium veins, and venules have valves to prevent the backflow of blood.
Step-by-step explanation:
True, large veins, medium veins, and venules have valves to prevent the backflow of blood. Veins are thin-walled vessels with large and irregular lumens. These low-pressure vessels rely on valves to promote the unidirectional flow of blood toward the heart and prevent backflow caused by low blood pressure and gravity.