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What happened to the first civilization developed in Mesopotamia?

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User Onera
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Answer:

Babylonian culture is considered to have ended under Persian rule, following a slow decline of use in cuneiform and other cultural hallmarks. By the time Alexander the Great conquered the Persian Empire in 331 B.C., most of the great cities of Mesopotamia no longer existed and the culture had been long overtaken.

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User Elbraulio
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