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_________ is the body's signal that the calories consumed earlier in the day have been used up.

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Hunger is the body's signal that the calories consumed earlier in the day have been used up. When the body has used up the energy from the last meal, the stomach empties and the blood sugar levels drop, triggering the release of hormones that signal the brain that it's time to eat again. This feeling of hunger is the body's way of telling us that it needs more fuel to function properly.
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User BluePsyduck
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Answer: hunger

Explanation

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User Kgibilterra
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