Question

Which of the following statements about the post-translation modification of proteins by phosphorylation are true?

Answer 1

1. Phosphorylation is the addition of a phosphate group to a protein.
2. Phosphorylation can alter the activity, localization, stability, and interaction of a protein.
3. The phosphate group is usually added to a serine, threonine, or tyrosine residue on the protein.
4. The addition of a phosphate group can create a new binding site for other proteins or molecules, allowing for new interactions.
5. Phosphorylation can be reversible, meaning the phosphate group can be removed by phosphatases, which can lead to the deactivation or altered activity of the protein.

All of the above statements about the post-translational modification of proteins by phosphorylation are true.