Question

inspect the structure of the following compounds and explain which one will elute first and which one will be last to elute

Answer 1

In the normal phase chromatography system described, the most nonpolar compound would elute first and the most polar compound would elute last. Why do large molecules elute first? The molecules that are larger than the pore volume will be eluted first due to their inability to penetrate the pores.

Step-by-step explanation:

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