Question

Eosinophils are bone marrow derived granulocytes that express Fc receptors when they are recruited to an inflammatory site. Only very small numbers of these cells are normally present in the circulation; most eosinophils are found in tissues, especially in the connective tissues immediately underneath respiratory, gut, and urogenital epithelium, implying a likely role for these cells in defense against invading organisms. What is an important regulator of the growth, survival, and function of eosinophils?

Fas receptor
IL-5
G-CSF
IL-8
RANTES

Answer 1

Interleukin-5 (IL-5) is the key regulator of eosinophil growth, survival, and function. It directs the production and mobilization of these cells, which play a crucial role in immune responses, particularly against parasitic worms and in allergic reactions.The correct option is B

Step-by-step explanation:

Eosinophils are bone marrow-derived granulocytes that are important components of the immune system, particularly in the fight against parasitic infections and in the response to allergies.

An important regulator of the growth, survival, and function of eosinophils is Interleukin-5 (IL-5). IL-5 is a cytokine that is critical for the development, differentiation, and mobilization of eosinophils from the bone marrow into the bloodstream and is instrumental in directing these cells to sites of inflammation.

These cells are specially equipped to combat parasites with their granules containing molecules toxic to parasitic worms, aiding in the body's defenses when an individual consumes raw or undercooked meat or is exposed to environments where parasitic worms may penetrate the integument.

Furthermore, eosinophils release antihistamines that counteract histamine from basophils and mast cells, substances that induce inflammation.

A higher eosinophil count can indicate allergies or parasitic infestation, while a lower count may be seen in conditions such as drug toxicity or stress.The correct option is B.