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One family of adhesion molecules induces "rolling" of leukocytes along blood vessel walls, an important first step in adhesion. What is this family known as?

a) Integrins
b) Selectins
c) Streptolysins
d) Immunophilins
e) Interleukins

1 Answer

6 votes

Final answer:

The family of adhesion molecules responsible for leukocyte 'rolling' along blood vessel walls is known as selectins, which are part of Intercellular Cell Adhesion Molecules.

Step-by-step explanation:

The family of adhesion molecules that induces the 'rolling' of leukocytes along blood vessel walls during the initial steps of adhesion is known as the selectins. Selectins are a type of Intercellular Cell Adhesion Molecules (ICAMs) that play a crucial role in the process of blood clotting as well as in immune responses. They enable the rolling interaction that is a precursor to firmer attachment and eventual transmigration of the leukocytes out of the bloodstream, a process called diapedesis.

The family of adhesion molecules known as Selectins induces the "rolling" of leukocytes along blood vessel walls, which is an important first step in adhesion. Selectins on one platelet recognize and bind specific receptors on other platelets, contributing to blood clotting. These molecules are part of the group of proteins called Intercellular Cell Adhesion Molecules (ICAMs), which are involved in binding cells together.

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User Volod
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