Final answer:
Novosibirsk is the largest city of Asian Russia on the Ob River, known for its industries and cultural significance.
Step-by-step explanation:
The largest city of Asian Russia on the Ob River is Novosibirsk. With a population of approximately 1.4 million people, it is not only Russia's third-largest city but also the most populous city in Asian Russia. Novosibirsk is known for its significant industries, as well as being a cultural hub; it boasts a music conservatory, a philharmonic orchestra, several major universities, and a division of the Russian Academy of Sciences. Its economic activities are diverse, spanning from agriculture and timber to mining.