Final answer:
High levels of corticotropin-releasing hormone (CRH) or cortisol are associated with anxiety and personality disorders in clusters A and B. These neurotransmitters are central to the body's response to stress and can lead to heightened states of arousal and anxiety. Antidepressants and other medications that affect CRH, cortisol, or their receptors can help ameliorate anxiety and dependency associated with these conditions.
Step-by-step explanation:
The neurotransmitter (NT) associated with anxiety and dependent traits commonly observed in clusters A and B personality disorders is likely to be corticotropin-releasing hormone (CRH) or cortisol. High levels of these substances in the central nervous system are often observed in individuals experiencing anxiety and those with certain personality disorders. CRH and cortisol are integral to the body’s stress response and play roles in anxiety disorders as they can lead to an increased state of hyperarousal and anxiety. Medications that modulate the effects of CRH, cortisol, or their receptors may help mitigate some of the symptoms associated with high levels of these substances, such as anxiety and dependency.
Research has indicated that certain genetic polymorphisms in the CRHR1 gene can influence the repsonse to antidepressants in anxious individuals. Additionally, the involvement of dopamine, serotonin (5-HT), and norepinephrine is also significant with regards to mood control and anxiety. Of particular note, serotonin and its receptors have been shown to play a role in the pathophysiology of affective and mood disorders, which includes anxiety-related behaviors.