Final answer:
Angiogenic growth factors, which assist in forming new blood vessels, are found in the periosteum. This membrane covers bones' external surfaces and plays a vital role in bone health, particularly during healing processes.
Step-by-step explanation:
The periosteum is known to contain angiogenic growth factors. Angiogenic growth factors are important for promoting the growth of new blood vessels, a process critical during bone repair and regeneration. The periosteum covers the outer surface of bones and provides an entry point for blood vessels and nerves, thus playing a central role in bone health and recovery after injuries.
The periosteum contains osteogenic cells which can differentiate into osteoblasts, the cells responsible for secreting osteoid (unmineralized bone matrix). Once osteoid is secreted around capillaries, it forms a trabecular matrix, and osteoblasts can become trapped in this matrix, turning into mature bone cells or osteocytes. Moreover, when growing portions of bones are being formed, including the deep layers of periosteum and endosteum, angiogenic factors are significant for vascularizing the new bone tissue.