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Vitamin __ has gained a rep as an "anti-infective" vitamin because so many of the body's defenses against infection depend on an adequate supply.

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Final answer:

Vitamin D is known as the 'anti-infective' vitamin because it is essential for overall immunity and aids in preventing infections. It also contributes to bone health, calcium absorption, and is associated with a reduced risk of certain cancers.

Step-by-step explanation:

The vitamin that has gained a reputation as an "anti-infective" vitamin is vitamin D. Its role is crucial for maintaining good health beyond just bone health. Vitamin D is paramount for general immunity against bacterial, viral, and fungal infections. Moreover, studies suggest an association between low levels of vitamin D and increased cancer risk. The integumentary system, including the skin, assists the immune system in defending the body against pathogens. The skin also plays a role in synthesizing vitamin D, which is necessary for calcium absorption in the digestive system.

Immune cells such as B and T cells have vitamin D receptors, which indicates the importance of vitamin D for the immune system's function. Inadequate vitamin D levels are linked to autoimmune diseases and immune deficiencies. While vitamins like C and E also play significant roles as antioxidants and help in the prevention of free radical damage, it's vitamin D that is specifically acclaimed for its anti-infective properties.

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