Question

What is the characteristic electroencephalographic pattern noted in Creutzfeldt-Jakob disease?

A. Three-per-second spike and wave
B. Periodic high-amplitude sharp wave complexes
C. Temporal spikes
D. Generalized background slowing
E. Periodic lateralizing epileptiform discharges (PLEDs)

Answer 1

The characteristic EEG pattern in Creutzfeldt-Jakob disease is Periodic high-amplitude sharp wave complexes.

Step-by-step explanation:

The characteristic electroencephalographic (EEG) pattern noted in Creutzfeldt-Jakob disease (CJD) is Periodic high-amplitude sharp wave complexes. These sharp wave complexes are also known as triphasic waves and are typically periodic with a repetition rate of 0.5 to 2 per second. The EEG appearance of CJD can be distinguished from other neurodegenerative diseases such as Alzheimer's or Huntington's by its rapid progression and these unique sharp wave complexes.