asked 161k views
1 vote
MR. G is receiving an oral antibiotic when it is determined that he is going to need nutritional supplementation as well. However, you are concerned that the nutritional supplement will decrease the absorption of this drug because of high gastric acid content or prolonged emptying time. What is the generic name of this antibiotic?

asked
User Arbuz
by
8.2k points

1 Answer

0 votes

Final Answer:

The generic name of the antibiotic in question is Tetracycline.

Step-by-step explanation:

Tetracycline, a broad-spectrum antibiotic, is known to have reduced absorption when taken alongside certain nutritional supplements due to interactions with high gastric acid content or prolonged emptying time. This reduced absorption can significantly impact the efficacy of the antibiotic.

When Tetracycline interacts with minerals such as calcium, magnesium, aluminum, or iron commonly found in nutritional supplements, it forms insoluble complexes, decreasing its absorption in the gastrointestinal tract. For instance, calcium-containing products like dairy or calcium supplements can bind with Tetracycline, reducing its bioavailability by up to 50%. Similarly, iron or magnesium supplements can interfere with Tetracycline absorption, affecting its therapeutic effectiveness.

The decrease in absorption happens due to chelation, where the antibiotic binds with metal ions, forming complexes that are poorly absorbed by the body. This interaction alters the chemical structure of Tetracycline, rendering it less effective against bacterial infections. To avoid this interference, it's recommended to separate the administration of Tetracycline from nutritional supplements by a few hours. This time gap minimizes the likelihood of interaction, allowing the antibiotic to be absorbed effectively without compromising its therapeutic benefits.

answered
User Ybrin
by
6.9k points
Welcome to Qamnty — a place to ask, share, and grow together. Join our community and get real answers from real people.