Final Answer:
B. dec. LOS tone,thus the correct option is (B).
Step-by-step explanation:
Maxalon, also known as metoclopramide, is a medication used to treat gastrointestinal issues, including nausea and vomiting. The given options (A, B, C, D, E) likely represent potential effects or actions associated with Maxalon. In this case, option B,dec. LOS tone, suggests a decrease in lower esophageal sphincter (LOS) tone,thus the correct option is (B).
The lower esophageal sphincter is a muscular ring that separates the esophagus from the stomach. Its tone, or the level of contraction, plays a crucial role in preventing stomach contents from flowing back into the esophagus. The decrease in LOS tone indicated by option B suggests a relaxation of this muscular ring. This effect can be relevant in the context of Maxalon's use, as it may help alleviate symptoms such as nausea by facilitating the passage of stomach contents into the intestines.
Understanding the pharmacological actions of Maxalon involves recognizing its impact on gastrointestinal motility. Metoclopramide acts as a prokinetic agent, enhancing the movement of food through the digestive system. One of its mechanisms is the stimulation of acetylcholine release, which, in turn, influences smooth muscle contractions, including the lower esophageal sphincter. Therefore, a decrease in LOS tone aligns with the medication's intended prokinetic effect. In summary, the correct answer is B, indicating a decrease in lower esophageal sphincter tone, aligning with Maxalon's prokinetic properties and its role in promoting gastrointestinal motility.