Question

How does sumatriptan stop the migraine before it happens?

A) By targeting serotonin receptors and constricting blood vessels
B) By reducing stress hormones in the brain
C) By enhancing dopamine production
D) By blocking inflammatory responses

Answer 1

Sumatriptan works by activating serotonin receptors on brain blood vessels, causing them to constrict and countering the vessel dilation that usually leads to migraines.

Step-by-step explanation:

Sumatriptan prevents migraines primarily by targeting serotonin receptors, which play a key role in the development of migraines. This medication binds to and activates the serotonin (5-HT) receptors on blood vessels in the brain, leading to vasoconstriction (the narrowing of blood vessels). As a result, it reverses the dilation that contributes to migraine headaches. Additionally, sumatriptan can have an effect on reducing the neuronal activity and blocking the release of pro-inflammatory substances that can lead to the pain and other symptoms associated with migraines.