Final answer:
The negative feedback loop is where the peripheral endocrine gland suppresses secretions of the anterior pituitary gland and hypothalamus hormones, maintaining homeostasis by preventing excessive hormone levels.
Step-by-step explanation:
The loop in which the peripheral endocrine gland suppresses the secretions of the anterior pituitary gland and hypothalamus hormones is referred to as a negative feedback loop. In this process, increased levels of hormones produced by target glands, such as the thyroid gland, signal the hypothalamus and anterior pituitary to reduce the production and release of their hormones. For example, the thyroid hormone's rise inhibits the production of thyroid-stimulating hormone (TSH) by the anterior pituitary and the thyrotropin-releasing hormone (TRH) by the hypothalamus. This regulation maintains homeostasis by preventing excessive hormone levels. The secretion of anterior pituitary hormones is controlled by the hypothalamus through releasing and inhibiting hormones that are transmitted via the hypophyseal portal system.