Question

Patients have different mutations in the same region but exhibit similar manifestations. What is the likely cause?

A) Spontaneous genetic mutations
B) Epigenetic modifications
C) Genetic anticipation
D) Founder effect

Answer 1

Patients exhibiting similar manifestations despite having different mutations in the same region may be due to epigenetic modifications.

Step-by-step explanation:

Patients exhibiting similar manifestations despite having different mutations in the same region may be due to epigenetic modifications. Epigenetics refers to changes in gene expression that are not caused by alterations in the DNA sequence itself, but rather by modifications to the DNA and its associated proteins. These modifications can affect how genes are turned on or off, leading to similar manifestations even with different mutations.