Final answer:
During meiosis, independent segregation refers to the random distribution of homologous chromosomes and independent assortment of different chromosomes, resulting in unique combinations of traits in gametes.
Step-by-step explanation:
During meiosis, independent segregation refers to the random distribution of homologous chromosomes to daughter cells and the independent assortment of different chromosomes. This process occurs during the first division of meiosis, known as meiosis I. Each pair of homologous chromosomes lines up randomly, leading to the potential for different combinations of chromosomes in gametes. This leads to the generation of unique combinations of traits in offspring.