Question

MOA of Amantadine (Symmetrel) (C)

Answer 1

Amantadine (Symmetrel) binds to a transmembrane protein involved in the escape of the influenza virus, preventing viral replication. It is also used for the treatment of Parkinson's disease.

Step-by-step explanation:

The mode of action of Amantadine (Symmetrel) is not entirely clear, but it appears to bind to a transmembrane protein that is involved in the escape of the influenza virus from endosomes. By blocking the escape of the virus, Amantadine prevents viral RNA release into host cells and subsequent viral replication.

Amantadine is also used for the treatment of Parkinson's disease due to its effects on brain chemicals such as dopamine and NMDA.