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How does biosynthesis of DNA viruses occur?

-Where does replication occur?
-What enzyme is used to transcribe genome?
-Viral or host encoded?

1 Answer

5 votes

Final answer:

DNA viruses replicate mainly using host cell machinery and enzymes within the nucleus, transcribing the viral genome into mRNA using host RNA polymerase. Reverse-transcribing viruses, like retroviruses, possess an RNA genome and use the enzyme reverse transcriptase for converting RNA into DNA.

Step-by-step explanation:

The replication of DNA viruses typically occurs in the nucleus of the host cell where it can access the host's DNA replication and transcription machinery. The enzyme used to transcribe the viral genome is usually the host's DNA-dependent RNA polymerase. However, there are instances where viral proteins may be required if the host lacks certain necessary enzymes for replication.

DNA viruses often rely on the host cell's machinery to replicate their DNA and to transcribe and translate that genome into viral proteins. In contrast, reverse-transcribing viruses, such as retroviruses, have an RNA genome and utilize the enzyme reverse transcriptase to convert their RNA into DNA, a process not found in uninfected host cells. An example of such a virus is HIV, which synthesizes its own reverse transcriptase that is targeted by specific antiviral drugs.

Overall, the biosynthesis of DNA and reverse-transcribing viruses is a complex interaction between viral and host cell components, leading to the production of new virions that can cause various diseases in humans, such as chickenpox and hepatitis B.

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User Glemiere
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