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A red, scaly skin rash may precede or follow joint inflammation in which of the following conditions?

a) psoriatic arthritis
b) rheumatoid arthritis
c) systemic lupus erythematosus
d) gout

1 Answer

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Final answer:

A red, scaly skin rash that may precede or follow joint inflammation is characteristic of psoriatic arthritis, a condition involving the immune system and skin cell interaction. Rheumatoid arthritis, systemic lupus erythematosus, and gout are other forms of joint diseases but they do not typically present with this type of skin rash associated with psoriatic arthritis.

Step-by-step explanation:

Psoriatic arthritis is the condition in which a red, scaly skin rash may precede or follow joint inflammation. The rash, characterized by itchy or sore patches of thick, red skin with silvery scales, can appear in various areas including elbows, knees, scalp, back, face, palms, and feet. Psoriatic arthritis involves the complex interaction between skin cells, immune cells, and inflammatory cytokines.

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease where the body's immune system attacks the synovial joints leading to inflammation and pain. RA symptoms include swollen, stiff, and painful joints, primarily affecting the hands, feet, and cervical spine. The disease is associated with autoimmune responses but does not commonly lead to a scaly skin rash.

Systemic lupus erythematosus (SLE) involves the body attacking its own tissues, including those in the joints, but it doesn't usually produce the characteristic rash seen in psoriatic arthritis unless it involves cutaneous lupus, which generally presents with a different type of rash. Finally, gout is an arthritic condition caused by the deposition of uric acid crystals in the joints, often leading to severe pain and swelling but not typically associated with a red, scaly skin rash.

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