Question

Which of the following would be a possible cause of a positive direct antiglobulin test?

A. Clot tube stored at 4°C
B. Transfusion reaction
C. Warm autoimmune disease
D. All of the above

Answer 1

A positive direct antiglobulin test (DAT) can be caused by a warm autoimmune disease or a transfusion reaction. The correct answer is D. All of the above.

Step-by-step explanation:

A positive direct antiglobulin test (DAT) indicates that antibodies have bound to the patient's own red blood cells. One possible cause of a positive DAT is a warm autoimmune disease, such as autoimmune hemolytic anemia, where the immune system mistakenly produces antibodies against its own red blood cells. Another possible cause is a transfusion reaction, where antibodies in the recipient's blood react with the donor's red blood cells. Therefore, the correct answer is D. All of the above.