Final answer:
The lower frequency of sickle-cell anemia among present-day Americans of West African ancestry as compared to people living in West Africa is attributed to genetic drift.
Step-by-step explanation:
The lower frequency of sickle-cell anemia among present-day Americans of West African ancestry as compared to people living in West Africa is attributed to genetic drift. Genetic drift refers to the random change in allele frequencies in a population over time. In this case, the movement of individuals from West Africa to the Americas during the slave trade resulted in a smaller population size and increased genetic drift, leading to a decrease in the frequency of the sickle-cell allele.