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____________ are the most important proteinases involved in the destruction of periodontal tissues

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User Piidro
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1 Answer

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Final answer:

Matrix metalloproteinases (MMPs) and plasmin are key enzymes in the degradation of extracellular matrix proteins, crucial for periodontal tissue destruction and remodeling.

Step-by-step explanation:

Matrix metalloproteinases (MMPs) are the most important proteinases involved in the destruction of periodontal tissues. These enzymes play a crucial role in the degradation of extracellular matrix (ECM) proteins such as collagen, fibrin, fibronectin, and laminin, which are critical to the structure and function of periodontal tissues. MMPs are known to be involved in ECM remodeling and degradation, participating in processes such as wound healing and tissue regeneration. Another significant enzyme is plasmin, which can degrade the provisional fibrin matrix formed during the onset of clotting, and also activate growth factors through specific cleavage events that may further influence tissue healing.

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User Ragoczy
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