Final answer:
Bloating is a side effect of biguanides due to their effects on the gastrointestinal tract, which can lead to increased gas production and changes in GI motility.
Step-by-step explanation:
The biguanides, such as metformin, are a class of drugs commonly used to treat type 2 diabetes. A common side effect associated with these medications is bloating. This occurs because biguanides can affect the gastrointestinal (GI) tract, leading to increased production of intestinal gases or changes in the motility of the GI tract. These alterations can result in discomfort, a feeling of fullness, and abdominal distension, which are symptoms typically described as bloating. Understanding and managing side effects are essential in medication adherence and optimal diabetes management. Bloating is a side effect of biguanides due to their effects on the gastrointestinal tract, which can lead to increased gas production and changes in GI motility.