Final answer:
Common tests performed on POCT include absorption screening, metabolic stability screening, in vitro cytochrome P450 inhibitory screening, plasma protein binding, and in vivo pharmacokinetic screening.
Step-by-step explanation:
Common tests that are performed on point-of-care testing (POCT) include:
- Absorption screening (n-octanol/water, PAMPA, Caco-2 cells)
- Metabolic stability screening (microsomes, hepatocytes)
- In vitro cytochrome P450 inhibitory screening (microsomes, human recombinant enzymes)
- Plasma protein binding (ultrafiltration, equilibrium dialysis)
- In vivo pharmacokinetic screening (cassette dosing, pooling samples)