Final answer:
The colleague should explore the client's resistance to taking medication to understand and address their concerns in a patient-centered manner. Major depressive disorder can be treated with multiple methods, including psychotherapy and various classes of antidepressants like MAO inhibitors and SSRIs.
Step-by-step explanation:
The next step a colleague should take when a client with a diagnosis of major depressive disorder expresses resistance to taking prescribed psychotropic medication is to D. explore with the client their resistance to taking medication. This is a key element of patient-centered care and may reveal underlying concerns or misconceptions that the client has about the medication. It is also important to ensure informed consent and that the client understands the risks, benefits, and alternatives to taking medication. With this understanding, the client may be more open to the idea or may need additional support in managing their depression through other therapeutic means. In dealing with major depressive disorder, there are multiple treatments available including psychotherapy, electroconvulsive therapy, deep-brain stimulation, and various classes of antidepressants such as MAO inhibitors and SSRIs, each working through different mechanisms.