Question

What is the importance of piRNAs being 5' monophosphorylated?

A)Stabilization of piRNA molecules
B)Facilitation of piRNA binding to mRNA
C)Enhancement of piRNA processing
D)Prevention of piRNA degradation

Answer 1

The 5' monophosphorylated structure of piRNAs is important for stabilizing piRNA molecules, facilitating piRNA binding to mRNA, and preventing piRNA degradation.

Step-by-step explanation:

The 5' monophosphorylated structure of piRNAs is important for several reasons:

1. Stabilization of piRNA molecules: The 5' monophosphate group helps protect piRNAs from degradation in the cytoplasm by exonucleases.
2. Facilitation of piRNA binding to mRNA: The 5' monophosphate group allows piRNAs to effectively bind to their target mRNAs, enabling the regulation of gene expression.
3. Prevention of piRNA degradation: The 5' monophosphorylated structure helps shield piRNAs from degradation, ensuring their stability and functionality.