Question

Which of the following details the correct sequence of events for RNA interference mediated by siRNA?

a) Export, dicing, loading, target binding
b) Dicing, loading, target binding, export
c) Loading, dicing, target binding, export
d) Target binding, dicing, loading, export

Answer 1

The correct sequence of events for RNA interference mediated by siRNA is: Loading, Dicing, Target binding, Export.

Step-by-step explanation:

The correct sequence of events for RNA interference mediated by siRNA is:

1. Loading
2. Dicing
3. Target binding
4. Export

First, the siRNA is loaded onto the RNA-induced silencing complex (RISC). Then, the double-stranded RNA is diced into shorter fragments by an enzyme called DICER. The antisense strand of the siRNA binds to complementary regions of the target mRNA, resulting in target binding. Finally, the cleaved mRNA is exported out of the cell.