Question

After miRNA diced, it associated with _____ to produce the _______.

A) Ribosomes, mature mRNA
B) Argonaute proteins, RNA-induced silencing complex (RISC)
C) RNA polymerase, mature miRNA
D) Spliceosomes, pre-miRNA

Answer 1

After miRNA is diced, it associates with Argonaute proteins to form the RNA-induced silencing complex (RISC), which plays a role in degrading target mRNAs.

Step-by-step explanation:

After miRNA is diced, it associates with Argonaute proteins to produce the RNA-induced silencing complex (RISC). miRNAs are short RNA molecules that are initially made in the nucleus as longer pre-miRNAs and then processed into mature miRNAs by an enzyme called Dicer. These mature miRNAs, along with RISC proteins, target and lead to the degradation of mRNAs that are old, no longer needed, or damaged during transcription, thus regulating gene expression post-transcriptionally.