Question

What're the 3 mechanisms of action of antifungals?

Answer 1

The 3 mechanisms of action of antifungals are disruption of ergosterol synthesis, binding to ergosterol, and targeting cell wall components.

Step-by-step explanation:

The 3 mechanisms of action of antifungals are:

1. Disruption of ergosterol synthesis:
2. Antifungal drugs interfere with the synthesis of ergosterol, which is a sterol found in fungal cell membranes but not in human cells. By targeting ergosterol synthesis, antifungals disrupt the function of the cell membrane.
3. Binding to ergosterol: Some antifungal drugs bind to ergosterol in fungal cell membranes, which disrupts the integrity of the membrane and leads to cell death.
4. Targeting cell wall components: Certain antifungal medications target specific components of the fungal cell wall, such as chitin.
5. By interfering with cell wall integrity, these drugs impair fungal growth and reproduction