Final answer:
DNA is wrapped around histones to form nucleosomes, contributing to the compact structure of chromatin and chromosomes.
Step-by-step explanation:
The relationship between DNA and histones can be represented as DNA : histone :: nucleosome : structure. In eukaryotes, DNA is wrapped around proteins called histones to form structures called nucleosomes. The histones, which consist of an octamer composed of four different histones, help in compacting and organizing the DNA. The nucleosomes, with their DNA coiled around them, stack compactly onto each other to form a 30-nm-wide fiber, which further contributes to the compact structure of chromatin and chromosomes.