Question

Porphyria cutanea tarda (PCT) - most common disorder of porphyrin (heme) synthesis - what enzyme is deficient? Major symptom?

Answer 1

The enzyme deficient in Porphyria cutanea tarda (PCT) is uroporphyrinogen decarboxylase. The major symptom of PCT is the development of blisters, erosions, and increased photosensitivity on sun-exposed areas of the skin.

Step-by-step explanation:

The enzyme deficient in Porphyria cutanea tarda (PCT) is called uroporphyrinogen decarboxylase.

PCT is the most common disorder of heme synthesis, specifically the synthesis of porphyrin.

The major symptom of PCT is the development of blisters, erosions, and increased photosensitivity on sun-exposed areas of the skin.