Final answer:
ACE-inhibitor induced angioedema and dry cough are due to the effects of ACE inhibitors on the renin-angiotensin-aldosterone system.
Step-by-step explanation:
ACE-inhibitor induced angioedema and dry cough are due to the effects of ACE inhibitors on the renin-angiotensin-aldosterone system.
ACE inhibitors block the action of the ACE enzyme, which normally converts angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor that increases systemic blood pressure.
By blocking the production of angiotensin II, ACE inhibitors cause vasodilation and a decrease in blood pressure, which can lead to angioedema (swelling of deeper layers of the skin) and dry cough.