Final answer:
Grapefruit juice significantly affects certain drugs by inhibiting liver enzymes and altering their metabolism. This can lead to higher levels of the drugs in the blood.
Step-by-step explanation:
The drugs that are significantly affected by grapefruit juice include:
- Rivaroxaban (Xarelto)
- Dabigatran (Pradaxa)
- Apixaban (Eliquis)
- Heparin (various)
- Warfarin (Coumadin)
Grapefruit juice contains compounds that can inhibit certain enzymes in the liver, which affects the metabolism of these drugs. This can lead to higher levels of the drugs in the blood, increasing their effectiveness or potential side effects.