Question

In which conditions is bupropion (Wellbutrin) contraindicated?

Answer 1

Bupropion (Wellbutrin) is contraindicated in individuals with a history of seizures, eating disorders, or those taking monoamine oxidase inhibitors (MAOIs).

Step-by-step explanation:

Bupropion (Wellbutrin) is contraindicated in certain conditions:

1. Seizure disorder: Bupropion lowers the seizure threshold, so it should not be used in individuals with a history of seizures or conditions that increase the risk of seizures, such as anorexia nervosa or bulimia.
2. Eating disorders: Bupropion carries a risk of weight loss, which can worsen eating disorders like anorexia nervosa or bulimia.
3. Monoamine oxidase inhibitor (MAOI) use: Bupropion should not be taken within 14 days of discontinuing an MAOI due to the risk of serotonin syndrome.