Final answer:
Loop diuretics inhibit the reabsorption of Na+ and Cl- ions, resulting in increased urination.
Step-by-step explanation:
Loop diuretics are drugs that inhibit the reabsorption of Na+ and Cl- ions in the loop of Henle, leading to increased urination. This is because the loop of Henle is responsible for reabsorbing water and electrolytes from the filtrate. By inhibiting the reabsorption of Na+ and Cl- ions, loop diuretics prevent the reabsorption of water, leading to increased urine volume. This can be beneficial in treating conditions like hypertension.