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Sympathetic innervation in gastrointestinal muscle:
excitatory or inhibitory?

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Final answer:

The sympathetic innervation in gastrointestinal muscle is inhibitory.

Step-by-step explanation:

The sympathetic innervation in gastrointestinal muscle is inhibitory.

The sympathetic division of the autonomic nervous system restricts the activity of enteric neurons, decreasing GI secretion and motility. This is part of the fight-or-flight response. On the other hand, parasympathetic activation stimulates enteric neurons, increasing GI secretion and motility, which is known as the rest-and-digest response.

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