Final answer:
Thrombolytic drugs such as alteplase, reteplase, and tenecteplase are used to dissolve blood clots. They work by converting plasminogen to plasmin, which breaks down fibrin. However, they can also cause potential toxicities such as bleeding and allergic reactions.
Step-by-step explanation:
Alteplase: Mechanism of action: Converts plasminogen to plasmin, which breaks down fibrin and dissolves blood clots. Clinical uses: Treatment of acute myocardial infarction (heart attack), and ischemic stroke. Potential toxicities: Bleeding, allergic reactions. Reteplase and Tenecteplase: Mechanism of action: Similar to alteplase. Clinical uses: Treatment of acute myocardial infarction. Potential toxicities: Bleeding, allergic reactions. Streptokinase: Mechanism of action: Forms a complex with plasminogen to convert it to plasmin. Clinical uses: Treatment of acute myocardial infarction, and deep vein thrombosis. Potential toxicities: Bleeding, allergic reactions.