Question

Prostaglandins, formed through the action of COX, can be converted to ____________ in platelets. This promotes vasoconstriction and thrombosis (formation of a blood clot)

a) Prostacyclin
b) Thromboxane A2
c) Leukotriene B4
d) Eicosapentaenoic acid

Answer 1

Prostaglandins synthesized by COX enzymes can be converted to Thromboxane A2 in platelets, leading to vasoconstriction and thrombosis.

Step-by-step explanation:

Prostaglandins, formed through the action of COX, can be converted to Thromboxane A2 in platelets. This promotes vasoconstriction and thrombosis (formation of a blood clot). Prostaglandin synthesis involves the conversion of arachidonic acid to prostaglandins using enzymes like cyclooxygenase (COX-1 and COX-2). Prostaglandins exhibit various biological activities including blood pressure regulation, and upon being converted to thromboxane A2 in platelets, they facilitate platelet aggregation and vasoconstriction.