Final answer:
The largest state in Mexico by area that most Americans associate with something very small is Chihuahua.
Step-by-step explanation:
The largest state in Mexico by area that most Americans associate with something very small is Chihuahua. Chihuahua is the largest state in Mexico, covering approximately 247,455 square kilometers (95,543 square miles). Despite its size, many Americans associate the name Chihuahua with the small dog breed, which is named after the state.