Question

Lipopolysaccharide is present in the outer membrane of gram negative bacteria. Which of the following does not apply to this?

A. It prevents phagocytosis
B. It promotes degranulation of PMN leukoccytes
C. It activates complement fixation
D. It has antigenic properties
E. It produces fever

Answer 1

Lipopolysaccharide (LPS) is found in the outer membrane of gram-negative bacteria and has a variety of effects, including the promotion of inflammation and fever, but it does not prevent phagocytosis.

Step-by-step explanation:

The lipopolysaccharide (LPS) is present in the outer membrane of gram-negative bacteria and is also known as endotoxin. It consists of Lipid A, which is responsible for its toxic properties, a core polysaccharide, and the O side chain or O antigen. One of the facts that does not apply to LPS is that it prevents phagocytosis. On the contrary, substances like the M protein in Streptococcus and mycolic acid in Mycobacterium tuberculosis are known to inhibit phagocytosis. LPS does play a role in promoting the degranulation of PMN leukocytes, activating complement fixation, being antigenic, and producing fever.